Lion’s Mane (Hericium erinaceus) stimulates neurite outgrowth and regeneration of damaged nerves. Its polysaccharides help with neuronal differentiation and promote neuronal survival. It has been found to help after ischemic strokes to prevent cell death and to help cells recover their health after loss of blood supply. Cognitive function scale scores increase continuously with intake of Lion's Mane.

Studies show that Lemon Balm was able to delay and/or completely prevent Alzheimer's processes in numerous test subjects. These studies showed that more than any other single botanical it helped a person cope with the demands of high workload, stress and lack of sleep which cause numerous free radicals to accumulate in the body and which take a big toll on brain cell. Lemon Balm helps by quenching those toxic free radicals before they damage brain tissue.

Bacopa monnieri (also called Brahmi or water hyssop) is an herb used since ancient times in Ayurvedic medicine. In ayuveda traditions, Bacopa enhances brain and memory function. Pharmacologicaaly speaking Bacopa has been shown to significantly increase levels of Vitamin C, Vitamin A, Vitamin E, and Glutathione in the brain. It also increased levels of selenium and zinc in the brain. These are important detoxifying and free radical quenching molecules. Several studies have found that Bacopa monnieri supplements can speed up information processing in your brain, reduce reaction times, improve memory and protect against Alzheimer's and other neurodegenerative processes.

Red Wine Concentrate is a dry powdered product with the same health benefits of wine without the alcohol. Red wine extract is one of the highest concentrated sources of the antioxidant Resveratrol. There are, however, many other polyphenols and anthocyanins that act as antioxidants in red wine. Interestingly, it would take 41 glasses of red wine to equal 20 mg of Red Wine concentrate (the amount in each serving of Cognitive Resilience).

Red Wine concentrate has been shown to protect against decline in neural activity in those parts of the brain that typically decline once dementia has begun. The is important because the earlier one intervenes with red wine concentrate supplementation the less damage will occur.

Curcumin (Turmeric) is Indian herb used from ancient times and still used in curry powder. It has been extensively studied in modern medicine and Indian systems of medicine for the treatment of various medical conditions, including cystic fibrosis, hemorrhoids, gastric ulcer, colon cancer, breast cancer, atherosclerosis, liver diseases and arthritis. It has been used in various types of treatments for dementia and traumatic brain injury.

• Curcumin has a potential role in the prevention and treatment of Alzheimer's Disease. Curcumin as an antioxidant, anti-inflammatory and lipophilic action improves the cognitive functions in patients with AD. A growing body of evidence indicates that oxidative stress, free radicals, beta amyloid, cerebral deregulation caused by bio-metal toxicity and abnormal inflammatory reactions contribute to the key event in Alzheimer's disease pathology. Due to various effects of curcumin, such as decreased Beta-amyloid plaques, delayed degradation of neurons, metal-chelation, anti-inflammatory, antioxidant and decreased microglia formation, the overall memory in patients with Alzheimer's Disease has improved
• Curcumin can boost brain-derived neurotrophic factor. One of the main drivers in the process of plasticity (making new brain connections, IE, learning) is brain-derived neurotrophic factor (BDNF).
• Curcumin has shown some promise in treating depression. In a controlled trial, 60 people with depression were randomized into three groups. One group took Prozac, another group took 1 gram of curcumin, and the third group took both Prozac and curcumin. After 6 weeks, curcumin had led to improvements similar to those of Prozac.